Immunoregulatory effect of mouse fetal neural cells on the graft-versus-host disease

Mouse models of graft-versus-host disease∗

the effect of explicit versus implicit error correction on writing of iranian intermediate efl learners

در این پایان نامه دو روش اصلاح اشتباهات نوشتاری زبان آموزان بزرگسال ایرانی در سطح متوسط مورد بررسی قرار می گیرد. در روش اول (explicit) اشتباهات بطور مستقیم و در روش دوم (implicit) اشتباهات بصورت غیر مستقیم اصلاح می شود. برای انجام این تحقیق از دو گروه 15 نفری استفاده شده است. به زبان آموزان در هر جلسه یک موضوع انشا داده شده است. این کار در 15 هفته (15 جلسه) تکرار شده است. مقایسه نتایج این آزمون...

CD4 CD25 Immunoregulatory T Cells: New Therapeutics for Graft-Versus-Host Disease

CD4 CD25 immunoregulatory T cells play a pivotal role in preventing organ-specific autoimmune diseases and in tolerance induction to allogeneic organ transplants. We investigated whether these cells could also control graft-versus-host disease (GVHD), the main complication after allogeneic hematopoietic stem cell transplantation (HSCT). Here, we show that the few CD4 CD25 T cells naturally pres...

Effect of HLA mismatch on acute graft-versus-host disease.

HLA matching between donors and recipients is the most important factor associated with acute graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation. With improvements in GVHD prophylaxis and supportive care, transplantations from HLA mismatched donors are performed increasingly frequently, drawing greater attention to the effects of HLA mismatch. In relat...

Effect of epigallocatechin-3-gallate on graft-versus-host disease.

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often complicated by alloreactive donor T-cell-mediated graft-versus-host disease (GvHD). The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), is an inhibitor of both DNA methyltransferase 1 (DNMT1) and signal transducer and activator of transcription 1 (STAT1), which are essential for induction of GvHD. Thus, in...